Differential gene expression in beta cells and non-beta cells from islets of NOD mice
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ABSTRACT: Diabetes (T1D) is a disease in which the immune system destroys the insulin-producing beta cells. Recently, researchers have become interested in the role of the innate immune system in initiating this process. To further investigate this, we used RNA-seq to analyze sorted beta cells from non-diabetic and pre-diabetic female non-obese models of diabetes (NOD). These results shed light on the potential involvement of m6A mediators in the development of T1D, highlighting a promising avenue for future research.
ORGANISM(S): Mus musculus
PROVIDER: GSE228219 | GEO | 2024/01/01
REPOSITORIES: GEO
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