Transcriptomics

Dataset Information

0

RNA-seq profiling of Drosophila larval ring glands of kdm5 null mutants


ABSTRACT: kdm5 is an essential gene in Drosophila that has critical developmental roles in the prothoracic gland cells of the larval ring gland. We performed a bulk transcriptome analysis of the larval ring gland in w[1118] (wild type) and kdm5[140] (null mutant) in order to identify genes in the prothoracic gland involved in the lethality of kdm5 null mutants. We found that the absence of kdm5 causes dysregulation of genes involved in various metabolic pathways. In particular, genes both bound by KDM5 and differentially expressed in this cell type are involved in regulation of mitochondrial biology and autophagy.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE229075 | GEO | 2023/10/16

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2023-10-16 | GSE229076 | GEO
| PRJNA952685 | ENA
| PRJNA952679 | ENA
2016-11-27 | GSE76304 | GEO
2021-03-16 | GSE159298 | GEO
| PRJNA952686 | ENA
2019-12-31 | GSE109201 | GEO
2016-06-08 | PXD004265 | Pride
2016-01-27 | PXD002771 | Pride
2015-12-22 | E-GEOD-70589 | biostudies-arrayexpress