Dataset Information

Proteomic analysis of prothoracic glands of the silkworm Bombyx mori

ABSTRACT: The project aim was to identify the cell membrane receptors that prothoracic gland cells use to decode and transduce information from the extracellular environment during the final larval stage of the model insect, Bombyx mori.

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Bombyx Mori (silk Moth)

TISSUE(S): Molting Gland, Steroid Hormone Secreting Cell

SUBMITTER: Skarlatos Dedos

LAB HEAD: Skarlatos G. Dedos

PROVIDER: PXD002771 | Pride | 2016-01-27

REPOSITORIES: Pride

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Publications

Reassessing ecdysteroidogenic cells from the cell membrane receptors' perspective.

Alexandratos Alexandros A Moulos Panagiotis P Nellas Ioannis I Mavridis Konstantinos K Dedos Skarlatos G SG

Scientific reports 20160205

Ecdysteroids secreted by the prothoracic gland (PG) cells of insects control the developmental timing of their immature life stages. These cells have been historically considered as carrying out a single function in insects, namely the biochemical conversion of cholesterol to ecdysteroids and their secretion. A growing body of evidence shows that PG cells receive multiple cues during insect development so we tested the hypothesis that they carry out more than just one function in insects. We cha ...[more]

PMID: 26847502

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