Transcriptomics

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Sex differences in the effects of caloric restriction (CR) on hepatic gene expression in mice


ABSTRACT: The effects of caloric restriction (CR) on glucose homeostasis and metabolic function differ between males and females. To investigate if hepatic function contributes to these sex differences, we collected liver samples from male and female C57BL/6NCrl mice that were fed ad libitum (AL) or underwent caloric restriction (CR; receiving 70% of daily AL intake) from 9-13 weeks of age. Livers were then analysed by bulk RNA-seq.

ORGANISM(S): Mus musculus

PROVIDER: GSE230402 | GEO | 2023/04/26

REPOSITORIES: GEO

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