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Identification of evolutionary mechanisms of myelomatous effusion by single-cell RNA sequencing

ABSTRACT: Myelomatous effusion (ME) is a rare manifestion of extramedullary multiple myeloma (MM) with limited therapeutic options and poor outcomes. To investigate the evolutionary mechanisms of ME, we used single-cell RNA sequencing to assess the transcriptomes of bone marrow, peripheral blood, and pleural effusion/ascites from three patients with ME.

ORGANISM(S): Homo sapiens

PROVIDER: GSE230510 | GEO | 2023/04/26

REPOSITORIES: GEO

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