Transcriptome profiling of genes regulated by RXR and its partners in monocyte-derived dendritic cells
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ABSTRACT: CD14+ human monocytes differentiating into DCs in the presence of IL4 and GM-CSF were treated with agonists for RXR and its partners or vehicle 18 hours after plating (experiment with RXR and permissive partners, donor 1-3) or 14 hours after plating (experiment with nonpermissive partners, donor 4-6). Cells were harvested 12 hours thereafter. Experiments were performed in biological triplicates representing samples from three different donors. In this study all probable RXR-signaling pathways induced by agonists for RXR, LXRs, PPARs, RAR and VDR were identified in differentiating human monocyte-derived dendritic cells.
ORGANISM(S): Homo sapiens
PROVIDER: GSE23073 | GEO | 2010/09/01
SECONDARY ACCESSION(S): PRJNA131679
REPOSITORIES: GEO
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