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Impact of the vitamin B12 on the transcriptional regulation of the Mycobacterium tuberculosis Complex

ABSTRACT: The transcriptome in response to vitamin B12 was interrogated in three M. tuberculosis Complex species: M. tuberculosis H37Rv, M. tuberculosis GC1237, and M. bovis AF2122/97. Examination of the core B12 transcriptome resulted in a robust differential regulation of 7 genes in the three species analysed

ORGANISM(S): Mycobacterium tuberculosis Mycobacterium tuberculosis variant bovis

PROVIDER: GSE232691 | GEO | 2023/12/22

REPOSITORIES: GEO

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Transcriptomic changes associated with growth of Mycobacterium tuberculosis H37Rv wild-type strain and ∆prpR mutant in mineral medium supplemented with cholesterol as the sole carbon source or standard medium supplemented with vitamin B12.

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