COPD basal cells are primed towards secretory to multi-ciliated cell imbalance driving increased resilience to environmental stressors

ABSTRACT: We characterized primary human bronchial epithelial cells (pHBECs) from end-stage COPD and pulmonary healthy individuals. The transcriptomic profiles were assessed by single cell analysis in serial samples of pHBEC culture focussing on basal cell differentiation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE233145 | GEO | 2024/04/01

REPOSITORIES: GEO