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SFANS RNAseq profiling of deep layer cortical cell types from human control and Huntington's Disease samples

ABSTRACT: The properties of the cell types that are most vulnerable in the Huntington's disease (HD) cortex have not been delineated. Here we have employed serial fluorescence activated nuclear sorting (sFANS) and deep molecular profiling to demonstrate that layer 5a pyramidal neurons are selectively vulnerable in primary motor cortex and other cortical areas.

ORGANISM(S): Homo sapiens

PROVIDER: GSE233408 | GEO | 2024/01/17

REPOSITORIES: GEO

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