Transcriptomics

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Transcriptomes of monocyte-derived DCs stimulated with various compounds


ABSTRACT: Little is known about the early transcriptional events in innate immune signaling in immature and tolerogenic monocyte-derived dendritic cells (DCs), the professional antigen-presenting cells of our immune system. TLR ligands usually induce a proinflammatory transcriptional response, whereas IL10 and/or dexamethasone induce a more tolerogenic phenotype. We used Affymetrix microarrays to obtain detailed information underlying pro- and anti-inflammatory transcriptional responsesand transcriptional networks in DCs

ORGANISM(S): Homo sapiens

PROVIDER: GSE23371 | GEO | 2011/07/08

SECONDARY ACCESSION(S): PRJNA131287

REPOSITORIES: GEO

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