Eukaryotic Initiation factor 4B is a multi-functional RNA binding protein that regulates histone mRNAs
Ontology highlight
ABSTRACT: In diffuse large B-cell lymphoma (DLBCL) poor outcome is associated with eIF4B-dependent stimulation of the DEAD box helicase eIF4A that unwinds RNA structures in 5’ untranslated regions (UTRs) in mRNAs that encode proteins with a role in cell proliferation. We carried out iCLIP to examine differences in RNAs bound by eIF4B in DLBCL-derived versus -control B-cells.
ORGANISM(S): Homo sapiens
PROVIDER: GSE233998 | GEO | 2024/09/04
REPOSITORIES: GEO
ACCESS DATA