Transcriptomics

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Meta-analysis of Single-cell RNA-seq Data Reveals the Formation of Tertiary Lymphoid Organ and Mechanism Heterogeneity in Vascular Disease


ABSTRACT: The role of different cells in intimal hyperplasia remains unintelligible. To characterize the cells in intimal hyperplasia, we performed single-cell RNA sequencing of whole remodeled vessel cells from C57BL/6J mice with a murine model of intimal hyperplasia at an early (IH 2w) or late stage (IH 4w). The single-cell RNA-seq analyses revealed the heterogeneity of cells in vascular remodeling.

ORGANISM(S): Mus musculus

PROVIDER: GSE234651 | GEO | 2023/10/04

REPOSITORIES: GEO

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