Project description:To investigate the effect of depletion of RALY on gene expression of A549 cells. We then performed gene expression profiling analysis using data obtained from RNA-seq.
Project description:To investigate the antitumor mechanism of LSD1 inhibitor B35 on NSCLC, we collected A549 cells treated with B35(2μM) for 72 hours, then we performed gene expression profiling analysis using data obtained from RNA-seq of control cells or B35 treatment group
Project description:A549 human lung cancer cells were knocked down with either siControl or siADGRF4. Gene expression levels were analyzed by RNA sequencing. ADGRF4 globally altered expression patterns of genes in A549 cells.
Project description:Fresh peripheral blood mononuclear cells of four human donors were cultured together with either lung adenocarcinoma A549 cancer cells or A549-expressing H1N1 Sialidase cancer cells. These treatments induced the differentiation of donor cells into immunosuppressive MDSC-like cells, which were further subjected to bulk RNA sequencing. Computational analysis of RNA-Seq profiles of these cells was applied to understand the differences in their suppressive capacities.
Project description:To investigate the function SF3B4 during the progression of lung cancer, A549 cells with either SF3B4 siRNA or scramble siRNA were used for RNA-seq.
Project description:To study the effect of rs1663689 on lung cancer cells, we generated A549(C/C) from A549(T/T) using CRISPR/Cas9 technology and performed RNA-seq.
