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Genome wide CRISPR screen in AML chemotherapy resistance.

ABSTRACT: Chemoresistance is the leading cause of acute myeloid leukemia (AML)-related deaths, and elucidation of the mechanisms of AML chemoresistance is necessary to effectively target this process. Here, we performed genome wide CRISPR-Cas9 screening to identify key molecules regulating AML chemoresistance.

ORGANISM(S): Homo sapiens

PROVIDER: GSE235688 | GEO | 2023/06/30

REPOSITORIES: GEO

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