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RNA-Seq Time-Course Analysis of NPCs Transcriptome in Response to HSV-1 Infection

ABSTRACT: The neurogenic niches within the central nervous system serve as essential reservoirs for neural precursor cells (NPCs), playing a crucial role in neurogenesis. However, these NPCs are particularly vulnerable to infection by the herpes simplex virus type 1 (HSV-1). In the present study, we investigated the changes in the transcriptome of NPCs in response to Herpes simplex virus 1 (HSV-1) infection. Using bulk RNA-Seq, the transcriptomes of HSV-1-infected NPCs were compared to those of uninfected samples at different time points in the presence or absence of antivirals.

ORGANISM(S): Homo sapiens

PROVIDER: GSE236646 | GEO | 2024/07/31

REPOSITORIES: GEO

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