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Mouse duodenal and ileal Paneth cell single cell RNA sequencing

ABSTRACT: An indepth analysis of Paneth cell transcriptome at single cell level has not been available. Existing intestinal epithelial cell scRNA dataset contain many cell types, where Paneth cells represent a small portion. We used a flow cytometry based approach to enrich and isolate relatively pure Panethc cells from a newly developed Paneth cell reporter mouse line (Lyz1-3'UTR-IRES-CreER; Rosa26R-tdTomato). Single cell RNA sequencing was performed on purified duodenal and ileal Paneth cells of mice housed under specific pathogen free condition.

ORGANISM(S): Mus musculus

PROVIDER: GSE237327 | GEO | 2023/09/01

REPOSITORIES: GEO

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Paneth cell scRNA-seq analysis of un-infected and Salmonella Typhimurium infected mice

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