USP2 inhibition prevents infection with ACE2- dependent coronaviruses in vitro and is protective against SARS-CoV-2 in mice
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ABSTRACT: In this study, we identified USP2 as a physiological deubiquitinase of ACE2 and USP2 inhibition led to ACE2 protein destruction, thereby preventing infections of coronaviruses that reliant on ACE2
ORGANISM(S): Mus musculus
PROVIDER: GSE237741 | GEO | 2023/12/08
REPOSITORIES: GEO
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