Telomerase is essential for cardiac differentiation and sustained metabolism of human cardiomyocytes
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ABSTRACT: The scRNA seq was performed on day 12 of hiPSC-cardiomyocyte differentiation protocol with 3 different conditions of telomere length at the hiPSC stage, namely- long telomeres, intermediate telomeres and short telomeres. The analysis showed expected clusters of the mesodermal lineage but a shift of clusters was observed depending upon the telomere legth status of the parent CRISPRi TERT hiPSCs used for differentiation
ORGANISM(S): Homo sapiens
PROVIDER: GSE239887 | GEO | 2024/04/25
REPOSITORIES: GEO
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