Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Epigenome analysis of normal and colorectal cancer (CRC) samples

ABSTRACT: Genome wide DNA methylation profiling of peripheral blood mononuclear cells(PBMCs) in normal and CRC samples. The Illumina Infinium 850k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 820,000 CpGs in PBMC samples. Samples included 50 newly diagnosed CRC patients and 50 normal controls. NOTE:Patients numbered "CRC" and "E-CRC" are from two wards of the same hospital and do not need to be treated differently in data analysis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE240324 | GEO | 2023/08/10

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Epigenome analysis of normal and lung adenocarcinoma (LUAD) samples

Project description:Genome wide DNA methylation profiling of peripheral blood mononuclear cells(PBMCs) in normal and LUAD samples. The Illumina Infinium 850k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 820,000 CpGs in PBMC samples. Samples included 35 LUAD patients and 50 normal controls.

2024-12-14 | GSE275371 | GEO

Epigenome analysis of normal and breast cancer(BC) samples

Project description:Genome wide DNA methylation profiling of peripheral blood mononuclear cells (PBMCs) in normal and BC samples. The Illumina Infinium 850k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 820,000 CpGs in PBMC samples. Samples included 50 newly diagnosed BC patients and 30 normal controls.

2023-07-20 | GSE237036 | GEO

Epigenome analysis of normal and gastric cardia cancer samples

Project description:Genome wide DNA methylation profiling of normal and gastric cardia cancer samples. The Illumina Infinium 850k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 850,000 CpGs in normal and gastric cardia cancer samples. Samples included 8 normal -gastrica cardia cancer paired tissues.

2023-01-01 | GSE200484 | GEO

Epigenome analysis of normal and PLK1 knockdown samples

Project description:The Illumina Infinium 850k Human DNA methylation Beadchip was used to obtain DNA methylation profiles in normal and PLK1 knockdown DU145 cell samples. Samples included normal and PLK1 knockdown DU145 cell samples, Each sample is repeated three times.

2022-02-22 | GSE167261 | GEO

Epigenome analysis of DU145 samples [II]

Project description:The Illumina Infinium 850k Human DNA methylation BeadChip was used to obtain DNA methylation profiles in DU145 cell samples. Samples included normal, PLK1 knockdown and UHRF1 knockdown DU145 cell samples. Each sample is repeated three times.

2022-10-31 | GSE185400 | GEO

Epigenome analysis of normal and ischemic stroke patients blood samples

Project description:Genome wide DNA methylation profiling of normal and ischemic stroke patients blood samples. The Illumina Infinium 850k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 850,000 CpGs in liquid. Samples included 3 healthy people blood samples, 3 ischemic stroke patients blood samples.

2022-09-28 | GSE197080 | GEO

Epi-genomewide study identifies epigenetic outliers in normal mucosa of colorectal cancer patients

Project description:Genome wide DNA methylation profiling of normal healthy patients and tumor and non-tumor samples of patients with colorectal cancer (CRC). The Illumina Infinium MethylationEPIC BeadChip was used to obtain DNA methylation across ~850,000 CpG sites. Samples include 78 normal sample from CRC patients, 76 tumor samples from CRC patients, and 68 samples from non-CRC patients

2022-03-23 | GSE199057 | GEO

Race-specific patterns of epigenetic aging and age-associated differential methylation in normal rectal biopsies: Implications for the biology of aging and its relationship to rectal cancer

Project description:Approximately 90% of colorectal cancer (CRC) develop over the age of 50, highlighting the im-portant role of aging in CRC risk. African Americans (AAs) shoulder a greater CRC burden than European Americans (EA), and are more likely to develop CRC at a younger age. The effects of aging in AA and EA normal rectal tissue have yet to be defined. Here, we performed epige-nome-wide DNA methylation analysis in the first, large-scale biracial cohort of normal rectum (n=140 samples)

2022-12-23 | GSE216024 | GEO

Genome-wide DNA methylation analysis of driver gene-negative and EGFR-mutation lung adenocarcinoma and ajacent normal tissue

Project description:Genome-wide DNA methylation profiling of normal and lung adenocarcinoma fresh tissue samples. The Illumina Infinium MethylationEPIC BeadChip (850K) was used to obtain DNA methylation profiles across 860,000 CpGs in fresh tissue of lung adenocarcinoma and adjacent histological normal lung tissue samples. Samples included 30 paired tumor-normal driver gene-negative lung adenocarcinoma tissues and 35 paired tumor-normal EGFR-mutation positive lung adenocarcinoma tissues.

2024-05-28 | GSE235414 | GEO