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Impact of Tle3 induced deletion on chromatin accessibility profile of effector memory CD8 cells

ABSTRACT: The goal of this study is to determine if central memory (Tcm) and effector memory (Tem) CD8 T cells can be reprogrammed to change their fate. We demonstrate that genetic ablation of Tle3 can promote generation of Tcm cells at the expense of Tem cells, and this can occur during the effector phase of the immune response.

ORGANISM(S): Mus musculus

PROVIDER: GSE241533 | GEO | 2023/10/10

REPOSITORIES: GEO

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