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Functional and molecular analysis of LMNA mutations related muscular dystrophy in zebrafish

ABSTRACT: LMNA mutations cause laminopathies, a group of rare genetic diseases with no known cure, only symptomatic treatment and supportive care. In this study, we characterized five LMNA mutations (LMNA(L35P), LMNA(A539V), LMNA(W520G), LMNA(E358K), and LMNA(R453W)) identified from patients diagnosed with muscular laminopathy in the zebrafish model.

ORGANISM(S): Danio rerio

PROVIDER: GSE242251 | GEO | 2023/09/08

REPOSITORIES: GEO

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Transcriptome analysis of C2C12 myoblasts with mutations in LMNA gene

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