Transcriptomics

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Gene expression profiling of human NK cells


ABSTRACT: To investigate novel molecular signatures and transcriptional regulators of immature and mature human NK cells, we performed whole-genome microarray analysis on dNK cells (CD3−CD56+), cNK cells (CD3−CD56+), pNK cells (CD3−CD56+), CD56+ T cells (CD3+CD56+) and T cells (CD3+CD56−). dNK cells were purified from first-trimester deciduas. cNK cells were purified from cord-blood mononuclear cells. pNK, CD56+ T and T cells were purified from adult peripheral blood mononuclear cells. Samples were collected from healthy adult donors after obtaining informed consent according to the Ethics Committee of the University of Science & Technology of China.

ORGANISM(S): Homo sapiens

PROVIDER: GSE24268 | GEO | 2013/02/10

SECONDARY ACCESSION(S): PRJNA133001

REPOSITORIES: GEO

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