Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptional profiling of CD4 T cells from control mice and from mice lacking BCL6 expression in CD4+ T cells 4+4

ABSTRACT: We isolated CD4+ T cells from mice vaccinated against, and challenged with, Brucella to investigate the function of CD4+ T cell intrinsic BCL6 signaling

ORGANISM(S): Mus musculus

PROVIDER: GSE243861 | GEO | 2024/01/24

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Transcriptional profiling of CD4 T cells from control mice and from mice lacking BCL6 expression in CD4+ T cells 4+2

Project description:We isolated CD4+ T cells from mice vaccinated against, and challenged with, Brucella to investigate the function of CD4+ T cell intrinsic BCL6 signaling

2024-01-24 | GSE243859 | GEO

Bcl6 controlled gene expression in naïve CD4 T cells (Tf0)

Project description:Gene expression data from wild-type and Bcl6-/- naive CD4 T cells In order to find genes regulated by Bcl6 in follicular helper T cells Naïve CD4 T cells were sorted from wild-type (WT) and T cell-specific conditional Bcl6-/- (KO) mice-- 8 samples, 4 WT and 4 KO

2015-04-08 | E-GEOD-67622 | biostudies-arrayexpress

Bcl6 controlled gene expression in naïve CD4 T cells (Tfh)

2015-04-08 | E-GEOD-67623 | biostudies-arrayexpress

Transcriptional profiling of CD4 T cells from control mice and from mice lacking BCL6 expression in CD4+ T cells

Project description:Transcriptional profiling of CD4 T cells from control mice and from mice lacking BCL6 expression in CD4+ T cells

| PRJNA1020181 | ENA

Bcl6 controlled gene expression in naïve CD4 T cells (Tfh)

Project description:Gene expression data from wild-type and Bcl6-/- naive CD4 T cells In order to find genes regulated by Bcl6 in follicular helper T cells

2015-04-08 | GSE67623 | GEO

Bcl6 controlled gene expression in naïve CD4 T cells (Tf0)

Project description:Gene expression data from wild-type and Bcl6-/- naive CD4 T cells In order to find genes regulated by Bcl6 in follicular helper T cells

2015-04-08 | GSE67622 | GEO

Transcriptional profiling of CD4 T cells from control mice and from mice lacking BCL6 expression in CD4+ T cells 4+4

Project description:Transcriptional profiling of CD4 T cells from control mice and from mice lacking BCL6 expression in CD4+ T cells 4+4

| PRJNA1020182 | ENA

Transcriptional profiling of CD4 T cells from control mice and from mice lacking BCL6 expression in CD4+ T cells 4+2

Project description:Transcriptional profiling of CD4 T cells from control mice and from mice lacking BCL6 expression in CD4+ T cells 4+2

| PRJNA1020178 | ENA

Population gene expression of anti-viral CD4 T cells in Bcl6 and Blimp1 deficient conditions

Project description:Population gene expression of effector CD4+ T cells WT, Bcl6-deficient , Blimp1-deficient or Bcl6 Blimp1-deficient was determined by RNAseq after LCMV Armstrong infection

2021-11-05 | GSE149597 | GEO

A role for BCL6 in maintaining CX3CR1+ CD4+ T cells during helminth infection

Project description:Distinct subsets of T lymphocytes express CX3CR1 under inflammatory conditions, but little is known about CX3CR1+ CD4+ T cells during Type 2 inflammation in helminth infections. Here, we used a fate-mapping mouse model to characterize CX3CR1+ CD4+ T cells during both acute Nippostrongylus brasiliensis and chronic Schistosoma mansoni helminth infections, revealing CX3CR1+ CD4+ T cells to be an activated tissue homing subset with varying capacity for cytokine production. Tracking these cells over time revealed that maintenance of CX3CR1 itself along with a TH2 phenotype conferred a survival advantage in the inflamed tissue. Single-cell RNA-sequencing analysis of fate-mapped CX3CR1+ CD4+ T cells from both the peripheral tissue and the spleen revealed a considerable level of diversity and identified a distinct population of BCL6+ TCF-1+ PD1+ CD4+ T cells in the spleen during helminth infections. Conditional deletion of BCL6 in CX3CR1+ cells result in fewer CX3CR1+ CD4+ during infection, indicating a role in sustaining CD4+ T cell responses to helminth infections. Overall, our studies revealed the behavior and heterogeneity of CX3CR1+ CD4+ T cells during Type 2 inflammation in helminth infections and identified BCL6 to be important in their maintenance

2023-08-12 | GSE239846 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data