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High Density Domain-Focused CRISPR Screens Reveal Novel Epigenetic Regulators of HOX/MEIS Activation in Acute Myeloid Leukemia [RNA-seq, SGF29 KO vs. NTC in MOLM13 and U937]

ABSTRACT: To investigate the transcriptomic effects upon loss of SGF29 in the AML cell lines U937 and MOLM13, we performed CRISPR knockouts, as well as transduction with non-targeting controls, and harvested samples for bulk RNA-Seq.

ORGANISM(S): Homo sapiens

PROVIDER: GSE243935 | GEO | 2024/10/31

REPOSITORIES: GEO

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