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BCL-2 modulates IRE1a activation to attenuate ER stress and pulmonary fibrosis

ABSTRACT: BCL-2 modulates IRE1a activation to attenuate ER stress and pulmonary fibrosis. Mice were treated with Bleomycin + Vehicle or Bleomycin + Navitoclax. Lungs were harvested 21 days after bleomycin injury followed by enzymatic digestion of the lungs to create single cell suspension and flow-sorting based isolation of total epithelial and stromal cells

ORGANISM(S): Mus musculus

PROVIDER: GSE244568 | GEO | 2024/03/04

REPOSITORIES: GEO

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BCL-2 modulates IRE1a activation to attenuate ER stress and pulmonary fibrosis

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