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Type III interferons induce pyroptosis in gut epithelial cells and delay tissue restitution upon intestinal injury

ABSTRACT: To investigate the transcriptional program within the intestinal epithelial cells (IECs) controlling the impact of type III interferons (IFN-λ) on intestinal recovery, we performed a single-cell RNA sequencing (scRNA-seq) on murine IECs following irradiation.

ORGANISM(S): Mus musculus

PROVIDER: GSE246333 | GEO | 2024/12/31

REPOSITORIES: GEO

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Type III interferons induce pyroptosis in gut epithelial cells and delay tissue restitution upon acute intestinal injury.

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