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Next Generation Sequencing of circRNAs in bladder cancer derived ITGA6+EVs

ABSTRACT: EVs served as crucial mediators preferably achieve their biological effect in recipient cells to create a supportive pre-metastatic niche via delivering distinct biomolecules, among which circular RNAs (circRNAs) with high stability and abundance in tumor derived EVs were under extensive exploration. Moreover, it is well-established that circRNAs play a significant role in BCa lymphatic metastasis. To explore the crucial circRNAs in BCa derived ITGA6+EVs, the ITGA6+EVs from total UM-UC-3-EVs were isolated by affinity capture using anti-ITGA6 magnetic beads and the circRNA expression profile was investigated using next-generation sequencing (NGS).

ORGANISM(S): Homo sapiens

PROVIDER: GSE246659 | GEO | 2024/10/10

REPOSITORIES: GEO

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