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Exploring Epigenetic Changes in the Development of Gemcitabine Resistance [SW1990R_vs_SW1990_RRBS]

ABSTRACT: To elucidate the DNA methylation alterations during the development of gemcitabine resistance in pancreatic cancer cells, we utilized both the parental SW1990 cells and their gemcitabine-resistant derivatives, SW1990R cells, to examine DNA methylation patterns. We employed reduced representation bisulfite sequencing (RRBS) assays to uncover the specific CpG methylation profiles.

ORGANISM(S): Homo sapiens

PROVIDER: GSE247167 | GEO | 2024/09/23

REPOSITORIES: GEO

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