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Microarray identification and characterization of differentially expressed microRNAs in pediatric ovarian immature teratoma

ABSTRACT: Ovarian immature teratoma (IM) is a type of germinal malignant tumor, affecting children, adolescents and young adults. Event-free survival is below 25% in high-grade IM. Pediatric IM is rare and seldom studied, raising controversial issues such as histopathological standard and lack of specific biomarkers. This study aimed to perform microRNA (miRNA) microarray and identify specific differentially expressed miRNAs in IMs than in other types of ovarian tumors. Our work enables practitioners to optimally exploit relevant characteristics for precise diagnostic and therapeutic strategies in IM.

ORGANISM(S): Homo sapiens

PROVIDER: GSE247518 | GEO | 2024/12/31

REPOSITORIES: GEO

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