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Targeting adipocyte ESRRA promotes osteogenesis and vascular formation in adipocyte-rich bone marrow

ABSTRACT: Extensive bone marrow adipocytes (BMAds) accumulation occurring under diverse pathophysiological conditions leads to bone deterioration.Estrogen-related receptor α (ESRRA) is a key regulator responding to metabolic stress.To explore the transcriptional role of ESRRA in regulating BMAds autonomous genes，bulk RNA-seq transcriptome analysis was performed in adipocyte-specific ESRRA deficiency BMAds lineage cells at 7 days upon adipogenic induction.

ORGANISM(S): Mus musculus

PROVIDER: GSE248799 | GEO | 2024/03/07

REPOSITORIES: GEO

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