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H3K9me3 and H4K29me3 CUT&Tag of therapy-induced senescent and diapause-like cancer cells

ABSTRACT: Analysis of the H3K9me3 and H4K20me3 differential localization over the genome of cancer cells in three conditions: proliferating cells, doxorubicin-treated cells (senescent) and INK128-treated cells (diapause-like). Two cell lines were used to perform the experiment: human melanoma SK-mel-147 cells and human NSCLC A549 cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE251660 | GEO | 2024/02/01

REPOSITORIES: GEO

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Transcriptomic analysis of therapy-induced senescent and diapause-like cancer cells

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Study the differential gene expression in SK-MEL-147 cells treated with different epigenetic modulator

Project description:The study evaluated the modulation of gene expression in SK-MEL-147 cell lines using different epegenetic modulator.

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Lentiviral shRNA library screen to identify growth-related genes in malignant melanoma

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