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An age specific platelet differentiation path from hematopoietic stem cells causes thrombocytosis and exacerbated thrombosis

ABSTRACT: Here we reveal a direct differentiation pathway from hematopoietic stem cells into platelets that is unique to aging. We used single cell RNA sequencing (scRNA-seq) to analyze age specific platelet pathway at the clonal level.

ORGANISM(S): Mus musculus

PROVIDER: GSE255019 | GEO | 2024/05/21

REPOSITORIES: GEO

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An age specific platelet differentiation path from hematopoietic stem cells causes thrombocytosis and exacerbated thrombosis

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