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The ERBB4 agonist JK07 Mitigates Atrial Remodeling and Inducibility of Atrial Fibrillation in Mice and Minipigs

ABSTRACT: To establish changes in cardiomyocyte transcription profiles brought about by atrial fibrillation, we collected left atrial appendage samples from minipig induced by DOCA or DOCA and JK07 and from vehicle samples. The transcriptional profile of mRNA in these samples will be measured with high throughput technology. Changes in transcriptional profiles can be correlated with the physiologic profile of atrial fibrillation acquired at the time of harverst.

ORGANISM(S): Sus scrofa

PROVIDER: GSE255166 | GEO | 2025/03/01

REPOSITORIES: GEO

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