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IGF2BP3 Inhibits Translation in Round Spermatozoa

ABSTRACT: To reveal the effects of IGF2BP3 on mouse spermatids at the post-transcriptional and translational levels, we performed RNA-seq and ribosome nascent-chain complex sequencing (RNC-seq) of spermatids from Igf2bp3+/- and Igf2bp3-/- mice after isolation. RNA-seq and RNC-seq sequencing showed that IGF2BP3 mainly plays a regulatory role in translational repression in spermatids.

ORGANISM(S): Mus musculus

PROVIDER: GSE256054 | GEO | 2025/02/05

REPOSITORIES: GEO

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