Gene expression profiling of Huh7 and THP1 cells after siRNA knockdown of C5/TRAF1 intergenic transcript

ABSTRACT: The C5/TRAF1 locus is a well validated genetic risk factor for RA. Upon further investigation of this region we recently discovered that the intergenic region between these two immune-related genes is activelly transcribed in a variety of tissues and is up-regulated in PBMCs, monocytes, B- and T-cells upon immune stimulation. The present study aimed to characterize the biological function of this newly identified C5/TRAF1 intergenic transcript, by analysing the effect of its knockdow on the gene expression profiles of Huh7 and THP1 cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE26067 | GEO | 2021/12/18

REPOSITORIES: GEO