Transcriptomics

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Fate mapping of human P63+ progenitor in vivo by single cell transcriptomic analysis [scRNA_seq]


ABSTRACT: KRT5+P63+ progenitor cells located in the basal layer of the airway epithelium have been identified as a promising candidate for lung epithelium repair. To gain molecular insights into the fate specification process of human P63+ progenitor cells in the lung, we sorted the transplanted GFP+ cells at different time points using flow cytometry, followed by 10x Genomics single-cell RNA sequencing analysis. Unsupervised clustering of the cells resulted in the identification of 7 distinct populations.

ORGANISM(S): Homo sapiens

PROVIDER: GSE260778 | GEO | 2024/12/19

REPOSITORIES: GEO

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