Transcriptomics

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Transcriptomic profiles of human aortic endothelial cell (HAOEC) which exposed to M(con) or M(Hb) macrophage supernatant


ABSTRACT: Cell phenotype switching is increasingly being recognized in atherosclerosis. Intraplaque hemorrhage (IPH) is thought to be a major contributor to plaque progression in part by stimulating the influx of CD163+ macrophages. We explored the hypothesis that CD163 macrophages cause plaque progression through the induction of pro-apoptotic endothelial to mesenchymal transition (EndMT) within the fibrous cap.

ORGANISM(S): Homo sapiens

PROVIDER: GSE262084 | GEO | 2024/04/30

REPOSITORIES: GEO

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