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Transcriptional changes following HIV infection of choroid plexus brain organoids

ABSTRACT: We employed iPSC-derived choroid plexus brain organoids to explore the impact of HIV infection on microglia, elucidating alterations in the host gene profile within the central nervous system. We conducted single-cell RNA sequencing to elucidate the changes in microglia upon HIV infection, leading to neural cell damage

ORGANISM(S): Homo sapiens

PROVIDER: GSE262349 | GEO | 2024/04/29

REPOSITORIES: GEO

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Transcriptional changes following HIV infection of choroid plexus brain organoids

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