Transcriptomics

Dataset Information

0

Endogenous Nodal switches Wnt interpretation from posteriorization to germ layer differentiation in geometrically constrained human pluripotent cells


ABSTRACT: We conducted bulk RNA sequencing on cells sorted by fluorescence from micropatterned colonies treated with FGF8 and different concentrations of WNT3a, using a SOX2::mCitrine cell line to distinguish between SOX2 positive and negative cells. The sequencing revealed that SOX2 negative cells exhibited a definitive endoderm identity, while SOX2 positive cells showed epiblast identity.

ORGANISM(S): Homo sapiens

PROVIDER: GSE263291 | GEO | 2024/04/09

REPOSITORIES: GEO

Similar Datasets

2021-06-30 | GSE173888 | GEO
2013-07-16 | GSE40641 | GEO
2021-11-04 | PXD028933 | Pride
2013-07-16 | E-GEOD-40641 | biostudies-arrayexpress
2018-08-27 | E-MTAB-6348 | biostudies-arrayexpress
| S-EPMC4423675 | biostudies-literature
2022-06-23 | PXD031272 | Pride
2016-07-28 | E-GEOD-84905 | biostudies-arrayexpress
2009-06-26 | GSE16801 | GEO
2013-05-10 | E-GEOD-46796 | biostudies-arrayexpress