Metastatic medulloblastoma remodels the local leptomeningeal microenvironment to promote further metastatic colonization and growth
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ABSTRACT: Medulloblastoma metastasis often occurs in the leptomeningeal spaces; however, the biology of the metastatic tumour cells and the local leptomeningeal niche are poorly characterized. We performed single-cell RNA sequencing to analyze the leptomeningeal metastatic niche in a medulloblastoma mouse model.
ORGANISM(S): Mus musculus
PROVIDER: GSE264326 | GEO | 2025/03/14
REPOSITORIES: GEO
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