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MATR3 Promotes Liver Cancer Progression by Suppressing DHX58–Mediated Type I Interferon Response

ABSTRACT: To investigate the mechanism of Matr3 in liver cancer, we stably knocked out Matr3 in Hepa1-6 cells and performed RNA sequencing with wild-type Hepa1-6 cells

ORGANISM(S): Mus musculus

PROVIDER: GSE264380 | GEO | 2025/04/01

REPOSITORIES: GEO

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MATR3 pathogenic variants differentially impair its cryptic splicing repression function

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The nuclear matrix protein MATR3 maintains higher-order chromatin architecture [Hi-C]

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