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New weapons explosive exhibits persistent toxicity in plants

ABSTRACT: Explosives are widespread, toxic and persistent environmental pollutants. 2,4-Dinitroanisole (DNAN) is being phased in to replace 2,4,6-trinitrotoluene (TNT) in munitions. Here we demonstrate that only low levels of DNAN are detoxified in Arabidopsis, leaving it to remain as a substrate for monodehydroascorbate reductase 6 mediated chronic phytotoxicity. Enhancing the potential for environmental toxicity, DNAN is readily transported to the aerial tissues exposing this toxin to herbivores and the wider food chain.

ORGANISM(S): Arabidopsis thaliana

PROVIDER: GSE264500 | GEO | 2024/10/29

REPOSITORIES: GEO

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Hazard Assessment of High-Nitrogen Compounds: Coupling Transcriptomics with Multi-Cellular Co-Culture Assays Provides Accurate Systemic Toxicity Screening [TNT]

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2011-06-22 | E-GEOD-30163 | biostudies-arrayexpress

Profiling differentially expressed earthworm genes in response to TNT, RDX, or TNT+RDX exposure.

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