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Transcriptomic analysis of cellular senescence induced by ectopic expression of ATF6α in human breast cancer cells

ABSTRACT: To investigate the molecular mechanism that triggers endoplasmic reticulum (ER) stress-induced cellular senescence in breast cancer cells, we established MCF7 cell lines exposed to ATF6α ectopic expression. We then performed gene expression profiling analysis using data obtained from RNA-seq of 9 different cells at three time points.

ORGANISM(S): Homo sapiens

PROVIDER: GSE270286 | GEO | 2024/11/06

REPOSITORIES: GEO

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