Transcriptomics

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Fish oil/pectin temporally alters gene expression profiles in exfoliated rat colonocytes throughout oncogenesis


ABSTRACT: We have demonstrated that fish oil/pectin (FO/P) diets protect against colon cancer compared to corn oil/cellulose (CO/C) by upregulating apoptosis and suppressing proliferation. To elucidate the mechanisms whereby FO/P diets induce apoptosis and suppress proliferation during the tumorigenic process, we analyzed the temporal gene expression profiles from exfoliated rat colonocytes. KEYWORDS: Fish oil/pectin, pectin, exfoliated colonocytes, gene expression, apoptosis, colon cancer, chemoprevention

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE27266 | GEO | 2012/02/20

SECONDARY ACCESSION(S): PRJNA137145

REPOSITORIES: GEO

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