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ScRNA-seq time-course of Coccidioides posadasii infected lungs

ABSTRACT: Coccidioidomycosis, or Valley Fever, is a lung disease caused by inhaling Coccidioides fungi, prevalent in the Southwestern U.S., Mexico, and parts of Central and South America. Climate change is contributing to the spread of this disease. Many cases are asymptomatic, some are often misdiagnosed, and a small subset can progress to severe illness. To better understand lung responses during Coccidioides infection, we used single-cell RNA sequencing (scRNA-seq). We analyzed non-infected lungs (D0) and infected lungs at 5, 9, and 14 days post-infection (D5, D9, D14).

ORGANISM(S): Mus musculus

PROVIDER: GSE274766 | GEO | 2024/11/13

REPOSITORIES: GEO

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Spatial Transcriptomics of Lungs Infected with Coccidioides posadasii

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