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Prenatal fetal head and placental gene expression in a mouse model of advanced maternal age

ABSTRACT: Advanced maternal age is a risk factor for neurodevelopmental disorders in offspring. The present study aimed to investigate differences in placental and fetal head gene expression between old and young C57BL6/J female mice. Conceptuses were collected at E12.5 and processed for transcriptomic mRNA gene expression microarray analyses. The most significant differences between old and young females were found in gene expression of the fetal heads (398 differentially expressed genes, DEG) as compared with the placenta (51 DEG).

ORGANISM(S): Mus musculus

PROVIDER: GSE276507 | GEO | 2024/09/26

REPOSITORIES: GEO

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