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Transcriptome of E10.5 WT and DDX3x-KO mouse hearts

ABSTRACT: Purpose: The goal of this study is to identify the differential mRNA tanscriptome between male and female E10.5 mouse hearts from Ddx3x KO female mice. Methods: miRNA profiles of male and female mouse hearts were generated by sequencing, n=3 for each genotype and sex using Illumina HiSeq2500. The sequence reads were aligned to the mm39 reference genome using STAR via the bcbio-nextgen RNA-sequencing pipeline. Differential gene expression was determined by EclipseBio. Results: Differentially expressed genes were identified between male and female samples, and separately with female wt and KO samples [ P value <0.05, |log2(Fold Change)| > 0.5].

ORGANISM(S): Mus musculus

PROVIDER: GSE276770 | GEO | 2025/04/01

REPOSITORIES: GEO

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