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Human Immune Exhaustion Gene Expression Profile in C7R-CAR and CAR NK cells

ABSTRACT: The purpose of this experiment was two-fold. The first was to examine how the gene expression profile changes over time in C7R-CAR NK cells. C7R is a constitutively active IL-7 receptor that provides persistent activation of STAT5. The second was to examine the differential gene expression in C7R CAR NK cells or CAR NK treated with exogenous IL-15 (exIL15) after 2 weeks of stimulation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE277499 | GEO | 2024/09/30

REPOSITORIES: GEO

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