Identifying of a novel RUNX1-RARA fusion in variant acute promyelocytic leukemia
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ABSTRACT: Here we report a novel fusion gene, RUNX1-RARA, in acute promyelocytic leukemia (APL). RUNX1-RARA triggers APL genesis by mediating transcriptional repression of target genes, and it can be potently restrained by all-trans retinoic acid treatment.
ORGANISM(S): Mus musculus
PROVIDER: GSE277794 | GEO | 2024/09/28
REPOSITORIES: GEO
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