Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

MiRNA Profiles of Long-Lived Individuals (>=90 years)

ABSTRACT: This project analyzes peripheral blood profiles of patients of age 90 or above and aims to detect profiles that distinguish them from younger controls.

ORGANISM(S): Homo sapiens

PROVIDER: GSE27905 | GEO | 2013/01/01

SECONDARY ACCESSION(S): PRJNA138219

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

miRNA Profiles of Long-Lived Individuals (>=90 years)

Project description:This project analyzes peripheral blood profiles of patients of age 90 or above and aims to detect profiles that distinguish them from younger controls. n = 55 normal controls and n = 15 long lived individuals have been screened for the complete miRNA repertoire. Please note that each miRNA has been measured in seven replicates and the median of the replica has been computed.

2013-01-01 | E-GEOD-27905 | biostudies-arrayexpress

Flavobacterium sp. 90 strain:90

Project description:Flavobacterium sp. 90 strain:90 Genome sequencing and assembly

| PRJNA442003 | ENA

Providencia alcalifaciens strain:2939/90 | isolate:2939/90

Project description:Providencia alcalifaciens strain:2939/90 | isolate:2939/90 Genome sequencing

| PRJNA929094 | ENA

BS-90 strain resistance in M-line Biomphalaria glabrata

Project description:Transcriptional profiles ofBS-90 snails sized 8-12mm exposed to E. paraensei (BS-90 are susceptible) and S. mansoni (BS-90 are resistant) and unexposed controls Keywords: Dose response

2010-08-01 | GSE21881 | GEO

Anabaena sp. 90 strain:90

Project description:Transcriptome of Anabaena sp. strain 90 under phosphorus limitation

| PRJNA276792 | ENA

Piscirickettsia salmonis EM-90

Project description:Piscirickettsia salmonis EM-90

| PRJNA231170 | ENA

Vibrio splendidus ZF-90

Project description:Vibrio splendidus ZF-90

| PRJNA167012 | ENA

Bradyrhizobium elkanii strain:USDA 90 | isolate:USDA 90

Project description:Bradyrhizobium elkanii USDA 90 genome sequencing

| PRJNA834273 | ENA

Subcortical volumes across the lifespan: Data from 18,605 healthy individuals aged 3-90 years.

Project description:Age has a major effect on brain volume. However, the normative studies available are constrained by small sample sizes, restricted age coverage and significant methodological variability. These limitations introduce inconsistencies and may obscure or distort the lifespan trajectories of brain morphometry. In response, we capitalized on the resources of the Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) Consortium to examine age-related trajectories inferred from cross-sectional measures of the ventricles, the basal ganglia (caudate, putamen, pallidum, and nucleus accumbens), the thalamus, hippocampus and amygdala using magnetic resonance imaging data obtained from 18,605 individuals aged 3-90 years. All subcortical structure volumes were at their maximum value early in life. The volume of the basal ganglia showed a monotonic negative association with age thereafter; there was no significant association between age and the volumes of the thalamus, amygdala and the hippocampus (with some degree of decline in thalamus) until the sixth decade of life after which they also showed a steep negative association with age. The lateral ventricles showed continuous enlargement throughout the lifespan. Age was positively associated with inter-individual variability in the hippocampus and amygdala and the lateral ventricles. These results were robust to potential confounders and could be used to examine the functional significance of deviations from typical age-related morphometric patterns.

| S-EPMC8675429 | biostudies-literature

Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3-90 years.

Project description:Delineating the association of age and cortical thickness in healthy individuals is critical given the association of cortical thickness with cognition and behavior. Previous research has shown that robust estimates of the association between age and brain morphometry require large-scale studies. In response, we used cross-sectional data from 17,075 individuals aged 3-90 years from the Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) Consortium to infer age-related changes in cortical thickness. We used fractional polynomial (FP) regression to quantify the association between age and cortical thickness, and we computed normalized growth centiles using the parametric Lambda, Mu, and Sigma method. Interindividual variability was estimated using meta-analysis and one-way analysis of variance. For most regions, their highest cortical thickness value was observed in childhood. Age and cortical thickness showed a negative association; the slope was steeper up to the third decade of life and more gradual thereafter; notable exceptions to this general pattern were entorhinal, temporopolar, and anterior cingulate cortices. Interindividual variability was largest in temporal and frontal regions across the lifespan. Age and its FP combinations explained up to 59% variance in cortical thickness. These results may form the basis of further investigation on normative deviation in cortical thickness and its significance for behavioral and cognitive outcomes.

| S-EPMC8675431 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data